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A Canonical 3-D P53 Network Model that Determines Cell Fate by Counting Pulses
(ISTANBUL UNIV, FAC ENGINEERING, 2018)
From a system theory perspective, p53 network dynamics is interesting since it can exhibit three dynamical modes of p53, namely low-level equilibrium, oscillation, and high-level equilibrium. Each of these modes are ...
Two-dimensional polynomial type canonical relaxation oscillator model for p53 dynamics
(INST ENGINEERING TECHNOLOGY-IET, 2018)
p53 network, which is responsible for DNA damage response of cells, exhibits three distinct qualitative behaviours; low state, oscillation and high state, which are associated with normal cell cycle progression, cell cycle ...
Aggregation for Computing Multi-Modal Stationary Distributions in 1-D Gene Regulatory Networks
(IEEE COMPUTER SOC, 2018)
This paper proposes aggregation-based, three-stage algorithms to overcome the numerical problems encountered in computing stationary distributions and mean first passage times for multi-modal birth-death processes of large ...
Revealing determinants of two-phase dynamics of P53 network under gamma irradiation based on a reduced 2D relaxation oscillator model
(INST ENGINEERING TECHNOLOGY-IET, 2018)
This study proposes a two-dimensional (2D) oscillator model of p53 network, which is derived via reducing the multidimensional two-phase dynamics model into a model of ataxia telangiectasia mutated (ATM) and Wip1 variables, ...
Data Dependent Stable Robust Adaptive Controller Design for Altitude Control of Quadrotor Model
(IEEE, 2018)
This paper presents Nonlinear Auto Regressive Moving Average (NARMA) based stable robust adaptive controller design. Both the plant and the closed-loop controller systems are modelled by the proposed NARMA based input-output ...
Two-dimensional polynomial type canonical relaxation oscillator model for p53 dynamics
(IET Systems Biology, 2018)
p53 network, which is responsible for DNA damage response of cells, exhibits three distinct qualitative behaviours; low state, oscillation and high state, which are associated with normal cell cycle progression, cell cycle ...
Aggregation for Computing Multi-Modal Stationary Distributions in 1-D Gene Regulatory Networks
(IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2018)
This paper proposes aggregation-based, three-stage algorithms to overcome the numerical problems encountered in computing stationary distributions and mean first passage times for multi-modal birth-death processes of large ...
Revealing determinants of two-phase dynamics of P53 network under gamma irradiation based on a reduced 2D relaxation oscillator model
(IET Systems Biology, 2018)
This study proposes a two-dimensional (2D) oscillator model of p53 network, which is derived via reducing the multidimensional two-phase dynamics model into a model of ataxia telangiectasia mutated (ATM) and Wip1 variables, ...
Effect of chaotic mixing on the rheological characterization of mayonnaise
(2017 10th International Conference on Electrical and Electronics Engineering, ELECO 2017, 2018)
In this study, a new mixing method for mayonnaise was developed. A chaotic hand mixer was designed. The speed of the mixer rotor was chaotically changed with the proposed method. Performance of the mixed mayonnaise was ...
A 2-dimensional model of polynomial type for oscillatory ATM-Wipl dynamics in p53 network
(2017 10th International Conference on Electrical and Electronics Engineering, ELECO 2017, 2018)
Under gamma irradiation, p53 gene regulatory network is able to exhibit three different modes, namely low state, oscillations, and high state. There are experimental studies demonstrating that oscillatory behaviour of p53 ...
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