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A Canonical 3-D P53 Network Model That Determines Cell Fate By Counting Pulses 

Demirkiran, G.; Kalayci Demir, G.; Guzelis, C. (2018)
From a system theory perspective, p53 network dynamics is interesting since it can exhibit three dynamical modes of p53, namely low-level equilibrium, oscillation, and high-level equilibrium. Each of these modes are ...
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A 2-Dimensional Model of Polynomial Type for Oscillatory ATM-Wip1 Dynamics in p53 Network 

Demirkiran, G.; Demir, G.K.; Guzelis, C. (IEEE, 2017)
Under gamma irradiation, p53 gene regulatory network is able to exhibit three different modes, namely low state, oscillations, and high state. There are experimental studies demonstrating that oscillatory behaviour of p53 ...
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A 2-dimensional Reduced Oscillator Model with Rational Nonlinearities for p53 Dynamics 

Demirkiran, G.; Demir, G.K.; Guzelis, C. (IEEE, 2017)
p53 tumour suppressor network plays the key role in DNA damage response of the cell. We present a comprehensive 2-dimensional oscillator model for p53 network dynamics. The model is reduced from the known 17-dimensional ...
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Investigation of Chaotic Mixing Performance on Characteristic Properties of Cake Batter 

Uzel, R.A.; Tugay Izmir, T.; Demirkiran, G.; Sahin, S.; Guzelis, C. (ELECO 2019 - 11th International Conference on Electrical and Electronics Engineering, 2019)
Chaotification is the process of making an originally non-chaotic system being chaotic by applying a suitable control input. The aim of the study was to create a chaotic mixing mechanism using a kitchen type mixer and to ...
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Stochastic Microgrid Control Problems: Effects of Load Distribution and Planning Horizon [Rassal Mikro Şebeke Kontrol Problemleri: Yök Daǧilimi ve Planlama Ufuk Uzunluǧunun Etkileri] 

Kahraman, A.; Bulut, O.; Biyik, E.; Guzelis, C.; Demirkiran, G. (Proceedings - 2019 Innovations in Intelligent Systems and Applications Conference, ASYU 2019, 2019)
Microgrids enable the integration of distributed energy resources with high renewable penetration into the main power grid. In this study, a microgrid problem that takes into account the stochastic nature of the net load, ...
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Coupling of cell fate selection model enhances DNA damage response and may underlie BE phenomenon 

Demirkiran, G.; Demir, G.K.; Guzelis, C. (IET Systems Biology, 2020)
Double-strand break-induced (DSB) cells send signal that induces DSBs in neighbour cells, resulting in the interaction among cells sharing the same medium. Since p53 network gives oscillatory response to DSBs, such interaction ...
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Demirkiran, G. (16)
Guzelis, C. (16)
Demir, G.K. (11)Sahin, S. (3)Uzel, R.A. (3)Izmir, T.T. (2)Biyik, E. (1)Bulut, O. (1)Genc, S. (1)Kahraman, A. (1)... View MoreDate Issued2018 (9)2019 (3)2017 (2)2020 (2)Has File(s)
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