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Aggregation for Computing Multi-Modal Stationary Distributions in 1-D Gene Regulatory Networks
(IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2018)
This paper proposes aggregation-based, three-stage algorithms to overcome the numerical problems encountered in computing stationary distributions and mean first passage times for multi-modal birth-death processes of large ...
Effect of chaotic mixing on the rheological characterization of mayonnaise
(2017 10th International Conference on Electrical and Electronics Engineering, ELECO 2017, 2018)
In this study, a new mixing method for mayonnaise was developed. A chaotic hand mixer was designed. The speed of the mixer rotor was chaotically changed with the proposed method. Performance of the mixed mayonnaise was ...
A comparison of feature selection algorithms for cancer classification through gene expression data: Leukemia case
(2017 10th International Conference on Electrical and Electronics Engineering, ELECO 2017, 2018)
In this study, three different feature selection algorithms are compared using Support Vector Machines as classifier for cancer classification through gene expression data. The ability of feature selection algorithms to ...
Two-dimensional polynomial type canonical relaxation oscillator model for p53 dynamics
(INST ENGINEERING TECHNOLOGY-IET, 2018)
p53 network, which is responsible for DNA damage response of cells, exhibits three distinct qualitative behaviours; low state, oscillation and high state, which are associated with normal cell cycle progression, cell cycle ...
Revealing determinants of two-phase dynamics of P53 network under gamma irradiation based on a reduced 2D relaxation oscillator model
(INST ENGINEERING TECHNOLOGY-IET, 2018)
This study proposes a two-dimensional (2D) oscillator model of p53 network, which is derived via reducing the multidimensional two-phase dynamics model into a model of ataxia telangiectasia mutated (ATM) and Wip1 variables, ...
A Canonical 3-D P53 Network Model that Determines Cell Fate by Counting Pulses
(ISTANBUL UNIV, FAC ENGINEERING, 2018)
From a system theory perspective, p53 network dynamics is interesting since it can exhibit three dynamical modes of p53, namely low-level equilibrium, oscillation, and high-level equilibrium. Each of these modes are ...
Aggregation for Computing Multi-Modal Stationary Distributions in 1-D Gene Regulatory Networks
(IEEE COMPUTER SOC, 2018)
This paper proposes aggregation-based, three-stage algorithms to overcome the numerical problems encountered in computing stationary distributions and mean first passage times for multi-modal birth-death processes of large ...
Revealing determinants of two-phase dynamics of P53 network under gamma irradiation based on a reduced 2D relaxation oscillator model
(IET Systems Biology, 2018)
This study proposes a two-dimensional (2D) oscillator model of p53 network, which is derived via reducing the multidimensional two-phase dynamics model into a model of ataxia telangiectasia mutated (ATM) and Wip1 variables, ...
Two-dimensional polynomial type canonical relaxation oscillator model for p53 dynamics
(IET Systems Biology, 2018)
p53 network, which is responsible for DNA damage response of cells, exhibits three distinct qualitative behaviours; low state, oscillation and high state, which are associated with normal cell cycle progression, cell cycle ...
A canonical 3-D P53 network model that determines cell fate by counting pulses
(Istanbul University - Journal of Electrical and Electronics Engineering, 2018)
From a system theory perspective, p53 network dynamics is interesting since it can exhibit three dynamical modes of p53, namely low-level equilibrium, oscillation, and high-level equilibrium. Each of these modes are ...