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A 2-Dimensional Model of Polynomial Type for Oscillatory ATM-Wip1 Dynamics in p53 Network
Under gamma irradiation, p53 gene regulatory network is able to exhibit three different modes, namely low state, oscillations, and high state. There are experimental studies demonstrating that oscillatory behaviour of p53 ...
A 2-dimensional Reduced Oscillator Model with Rational Nonlinearities for p53 Dynamics
p53 tumour suppressor network plays the key role in DNA damage response of the cell. We present a comprehensive 2-dimensional oscillator model for p53 network dynamics. The model is reduced from the known 17-dimensional ...